Study on the Effect and Its Mechanism of Fuzheng Jiedu Quyu Formula Combined with Oxaliplatin on Proliferation and Apoptosis of Human Colon Cancer HT-29 CellChinese Full TextEnglish Full Text (MT)
ZHAO Xiumei;ZHOU Bing;ZHANG Guixian;CHAI Zhongqiu;LIU Xiaoyun;LIU Hongbin;Tianjin Institute of Medical and Pharmaceutical Sciences;Dept. of Anorectal,TCM Hospital of Tianjin Binhai New Area;
Abstract: OBJECTIVE:To study the effect and its mechanism of Fuzheng Jiedu Quyu formula(short for"Fuzheng formula")combined with oxaliplatin(L-OHP)on human colon cancer HT-29 cell proliferation and apoptosis. METHODS:HT-29 cells were divided into blank control group(without drugs),Fuzheng formula group(1 000 mg/L),L-OHP group(31.25 mg/L)and combination group(1 000 mg/L Fuzheng formula+31.25 mg/L L-OHP). After cultured with corresponding drug for 48 h,MTT method was used to detect the cell proliferation;th... More
Keywords:
Fuzheng Jiedu Quyu formula; Oxaliplatin; Human colon cancer HT-29 cell; Proliferation; Apoptosis; in vitro;
- Series:
(E) Medicine & Public Health
- Subject:
Oncology
- Classification Code:
R735.35
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