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China Journal of Traditional Chinese Medicine and Pharmacy. 2019, (10) Core

Identification and verification of potential biomarkers associated with different syndromes of steroid-induced osteonecrosis of the femoral head based on gene expression profilesChinese Full TextEnglish Full Text (MT)

LI Tai-xian;ZHANG Yan-qiong;XUE Zhi-peng;WANG Rong-tian;LIU Dao-bing;LI Shang-zhu;CAO Yu-ju;LIN Na;CHEN Wei-heng;Wangjing Hospital of China Academy of Chinese Medical Sciences;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences;Institute of Hematology ＆ Blood Diseases Hospital of China Academy of Chinese Medical Sciences;Zhengzhou Traditional Chinese Medicine Traumatology Hospital;

Abstract: Objective: To identify potential biomarkers for the different syndromes of steroid-induced osteonecrosis of the femoral head（SONFH）. Methods: A total of 60 SONFH patients and 20 controls were enrolled in the present study. All the samples were divided into a discovery cohort and validation cohort（40 per group） randomly. The gene expression profile was detected by microarray analysis based on the discovery cohort. Then, the syndrome-related molecular interaction networks were constructed to ident... More
Keywords：

Steroid-induced osteonecrosis of the femoral head; Gene expression profiling; Biological molecular network; Biomarker;

  • Series：

    (E) Medicine ＆ Public Health

  • Subject：

    Traditional Chinese Medicine

  • Classification Code：

    R274.9

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