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Chinese Pharmaceutical Journal. 2009, (05) Core

Simultaneous Quantitative Analysis of Five Alkaloids in Rhizoma of Coptis chinensis by Multi-Components Assay by Single MarkerChinese Full Text

KUANG Yan-hui1,2,ZHU Jing-jing1,WANG Zhi-min1,ZHANG Qi-wei1(1.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;2.College of Pharmacy,Hunan University of Traditional Chinese Medicine,Changsha 410004,China)

Abstract: OBJECTIVE To establish a new method of quality evaluation and validate its feasibilities by the simultaneous quantitative assay of five alkaloids in rhizome of Coptis chinensis.METHODS The new quality evaluation method,quantitative analysis of multi-components by single marker（QAMS）,was established and validated with rhizoma of Coptis chinensis.Five main alkaloids,berberine,palmatine,coptisine,epiberberine and jatrorrhizine,were selected as analytes to evaluate the quality.Their contents in 28 b... More
Keywords：

quantitative analysis multi-components by single marker（QAMS）; related correction factor（RCF）; HPLC; Optis chinensis; alkaloid;

  • Series：

    (E) Medicine ＆ Public Health

  • Subject：

    Traditional Chinese Medicinal Herbs

  • Classification Code：

    R284

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