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Chinese Traditional and Herbal Drugs. 2020, (11) Core Bilingual

Mechanism of Tanreqing Capsule on treatment of coronavirus disease 2019 based on network pharmacologyChinese Full TextEnglish Full Text (MT)

HAN Yan-qi;LIU Yao-chen;WU Qi;XU Jun;ZHANG Tie-jun;MU Jing-wei;LIU Chang-xiao;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research;Tianjin Medical University;Shanghai Kaibao Pharmaceutical Co., Ltd.;

Abstract: Objective To explore the network regulation mechanism of Tanreqing Capsule（TRQC） on the treatment of coronavirus disease 2019（COVID-19）. Methods Potential targets of the 19 major constituents in TRQC were predicted by the Swiss Target Prediction server and TCMSP database. Gene ontology（GO） function enrichment and pathway analysis of the targets were analyzed by Omicsbean analytic system and String 10 database. Finally, Cytoscape 3.6.1 software was used to construct the network pharmacology map. ... More
Keywords：

Tanreqing Capsule; coronavirus disease 2019; network pharmacology; mechanism; scutellarin; baicalin; oroxylin-7-O-glucuronide; chrysin-7-O-glucuronide; forsythin; forsythiaside E; forsythiaside D; chlorogenic acid; caffeic acid; isochlorogenic acid A; ursodeoxycholic acid; chenodeoxycholic acid;

  • Series：

    (E) Medicine ＆ Public Health

  • Subject：

    Traditional Chinese Medicine

  • Classification Code：

    R259

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