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Acta Physiologica Sinica. 2018, (05) Core

The regulation of Na+/H+ exchangers by Toll-like receptors under inflammationChinese Full Text

CHE Hao;RUAN Yu-Yan;LUO Tang-Yan;CHEN Ming-Min;Medical School, Shaoxing University;

Abstract: Toll-like receptors（TLRs） can be recognized and activated by different pathogen associated molecular patterns（PAMPs）, which induce innate immune response and inflammation of the body. Na+/H+ exchangers（NHEs） not only play roles in the regulation of cellular pH and cell volume, maintenance of the cavity microenvironment and nutrients absorption, but also are related to cell proliferation, migration and apoptosis. The activity and membrane protein expression of NHEs are inhib... More
Keywords：

Toll-like receptors; Na+/H+ exchanger; infection; inflammatory bowel disease;

  • DOI：

    10.13294/j.aps.2018.0069

  • Series：

    (E) Medicine ＆ Public Health

  • Subject：

    Fundamental Medicine

  • Classification Code：

    R364.5

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