Amidolitic Method with Chromogenic Substrate for Determining the Activity of Low Molecular Weight Heparin Sodium InjectionChinese Full Text
XIE Ji Qing ①,LIANG Ai Jun ②,YU Yan Li,YUAN Cheng ( ①Department of Pharmacy,General Hospital of Jinan Command,Ji’nan 250031,Shandong China) ( ②Institute for Drug and Instrument Control of Health Dept GLD of PLA,Beijing 100071 China)
Abstract: Aim To determine the anti-FⅩa activity of low molecular weight heparin sodium injection.Methods Use the amidolitic method with chromogenic substrate.Results This method compared with the standard method had no evident difference.The activities of four group of low molecular weight heparin sodium injection determined by this method were 4 475,4 933,4 841 and 5 130 IU respectively,as 89.5%,98.6%,96.8% and 102.6% as the scalar quantity.Conclusion This measurement was exact and feasible.
- Series：
(E) Medicine ＆ Public Health
- Subject：
Pharmaceutics
- Classification Code：
R927
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