Effect of Smac/DIABLO Overexpression on Apoptosis of Human Colonic Cancer Cells
GAO Fei GUO Wen WANG Ji-de Institute of Gastroenterology,Southern Hospital,Southern Medical University,Guangzhou 510515
Abstract: Background Smac/DIABLO,a mitochondrial protein that promotes cell apoptosis,is low-expressed in colonic cancer cells. Objective To investigate the effect of Smac/DIABLO on the growth of human colonic cancer cells and its potential mechanism on cell apoptosis.Methods Human colonic cancer cell line LoVo was transfected with plasmid pcDNA3.1-Smac and plasmid pcDNA3.1, respectively by using Lipofectamine2000,and untreated LoVo cells served as blank controls.Reverse transcriptase polymerase chain rea... More
Conference Name：
第九届国际治疗内镜和消化疾病学术会议
Conference Time：
2008-04
Conference Place：
中国河南郑州
- Series：
(E) Medicine ＆ Public Health
- Subject：
Oncology
- Classification Code：
R735.35
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