Background and objectives: The migration in Chile increased by 28% between the years 2012 and 2015. As there are no studies in the country that describe the pre-pregnancy nutritional status (NS) and perinatal outcomes of immigrant (GI) versus Chilean (GI) pregnant women, the objective of this study was to compare the NS and to analyze its association with maternal and newborn pathologies in GNI versus GI who attended their delivery at the Hospital Clinico San Borja Arriaran (2015). Methods: A comparative study carried out at 1,078 GI and 1,520 GNI. The data were obtained from: 1. the clinical records 2. The health agenda and a survey made to the pregnant woman. The variables studied were NS (underweight, normal, obesity and overweight) determined by Atalah standard; Gestational diabetes (GD), preeclampsia (PE), intrauterine growth retardation (IUGR) and preterm birth (PTB). Data were presented as prevalences and compared with CHI2 test. Crude and adjusted (by sociodemographic, obstetric and of maternal diseases variables) logistic regression models were performed to evaluate the association between NS and maternal and newborn pathologies. Results: The GNI had significantly more likely to have obesity 3.0 [2.4 - 3.8] and overweight 1.7 [1.4 - 2.1] at the beginning of gestation than GI, in relation to have a normal nutritional status (50% GI and 34% In GNI, p <0.001), with no differences in the risk of underweight 1.1 [0.8 -1.5]. GI had a higher prevalence of anemia than GNI (12.6% vs 7.7, p <0.001). On the other hand, the GNI had higher prevalences of GD (8.7% vs 4.4%, p <0.001) and preeclamsia (8.3% vs 4.9%, p <0.05) than GI, while their children had a higher prevalence of PTB (14.0% vs. 6.6%, p <0.001) and IUGR (6.9% vs. 3.7%, p <0.001) than GI. Crude and adjusted logistic regression models showed that GD was associated with maternal obesity and overweight; PE was associated with obesity; while maternal underweight was associated with IUGR. Conclusions: The GNI presented higher prevalences of obesity, DG, PE, IUGR and PTB than GI. Obesity was associated with DG and PE and the latter with PTB. characteristic marker bands of three iron–sulfur clusters in four different states of the oxygen‐tolerant membrane‐bound hydrogenase can be disentangled by combining resonance Raman spectroscopy of protein crystals with protein engineering and crystallography.
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