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Chinese Bulletin of Life Sciences. 2022, (10) Core

The application of gene editing in disease diagnosisChinese Full TextEnglish Full Text (MT)

WANG Xin-Ge;MAO Bang-Wei;LI Wei;State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences;Institute for Stem Cell and Regeneration, Chinese Academy of Sciences;University of Chinese Academy of Sciences;

Abstract: Prompt and correct treatment of disease depends on detection and diagnosis. Molecular diagnosis has been playing an increasingly important role in disease diagnosis because of its sensitivity, convenience and early screening window. Based on the application of gene editing technology in disease diagnosis, in this paper, on the one hand, we explain the common working principle of gene editing technology in diagnosis, and on the other hand,discuss the application of gene editing in disease diagnos... More
Keywords：

gene editing; disease detection; molecular diagnosis; screening detection; POCT;

  • DOI：

    10.13376/j.cbls/2022136

  • Series：

    (A) Mathematics/ Physics/ Mechanics/ Astronomy; (E) Medicine ＆ Public Health

  • Subject：

    Biology; Clinical Medicine

  • Classification Code：

    R440;Q78

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