Molecular Simulation of HIV-1 Protease Inhibitors Activity of 3,9-Diazaasteranes
Zhi-Gang Peng,Hong Yan*,Ru-Gang Zhong College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100022
Abstract: 3, 9-diazaasteranes were verified as a HIV-1 protease inhibitor with an excellent biologic activity and how to design a more active HIV-1 protease inhibitor is a big challenge to us. We design a series of 3, 9-diazaasteranes by the molecular docking, and the result of the molecular docking show that the novel 3, 9-diazaasteranes maybe have more excellent activity than which were reported.
Keywords：
Conference Name：
中国化学会第二十五届学术年会
Conference Time：
2006-07
Conference Place：
中国吉林长春
- Series：
(E) Medicine ＆ Public Health
- Subject：
Pharmaceutics
- Classification Code：
R91
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