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(Accepted Version) Online First Publishing Date: 2024-11-01 16:48:25

Research Progress of Transporter-Mediated Drug-Drug Interaction Studies in New Drug DevelopmentChinese Full TextEnglish Full Text (MT)

FU Shujun;XIA Bin;SILuqin;HUANG Jiangeng;

Abstract: There are a large number of drug transporters widely distributed in various tissues and organs in human. They are involved in the membrane transport of numerous endogenous substances， toxins， and drugs. The transmembrane transport mediated by transporters not only plays an important role in maintaining the homeostasis of the internal environment， but is also closely related to drug absorption， distribution， metabolism， and excretion processes. In clinical practice， drug-drug/endogenous molecule ... More
Keywords：

Transporters; Drug-drug interaction; U.S.Food and Drug Administration; New drug development;

  • Series：

    (E) Medicine ＆ Public Health

  • Subject：

    Pharmaceutics

  • Classification Code：

    R969.2

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