Inhibitory effect of eugenol on myocardial ischemia-reperfusion injury in rats and its mechanismChinese Full Text
ZHU Qiumeng;SHI Jiaqi;LYV Wei;ZHANG Xin;XIAO Yunfeng;School of Pharmacy, Inner Mongolia Medical University;
Abstract: Objective To investigate the inhibitory effect of eugenol on myocardial ischemia-reperfusion injury（MIRI） in rats and to analyze its mechanism. Methods Wistar rats were randomly divided into sham operation group, MIRI model group, low-dose eugenol group, medium-dose eugenol group, high-dose eugenol group, and positive control group, with 10 rats in each group. Rats in the low-dose eugenol group, medium-dose eugenol group, and high-dose eugenol group were given 50, 100, and 200 mg/（kg·d） eugenol ... More
Keywords：
eugenol; myocardial ischemia-reperfusion injury; transcriptome; hypoxia inducible factor-1 signaling pathway;
- Series：
(E) Medicine ＆ Public Health
- Subject：
Traditional Chinese Medicinal Herbs
- Classification Code：
R285.5
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