Establishment, optimization and practice of an automatic central nervous system adverse reactions monitoring module based on hospital information system dataChinese Full Text
LI Haiyan;GUO Daihong;ZHU Man;GAO Ao;LU Jingchuan;FU An;LI Chao;LI Peng;ZHAO Anqi;Department of Pharmacy, Medical Supplies Center of PLA General Hospital;College of Pharmacy, Chongqing Medical University;
Abstract: Objective To construct a module for drug-induced central nervous system adverse reactions（CNS-ADR） within the Clinical Adverse Drug Event Active Monitoring and Intelligent Assessment Alert System-II（ADE-ASAS-II）, and to conduct a large-scale, real-world active monitoring and evaluation of CNS-ADR specifically related to imipenem/cilastatin. Methods Based on literature review, spontaneous report evaluation, and initial word set of CNS-ADR related descriptions in electronic medical records, text r... More
Keywords：
Central nervous system; Adverse drug reaction; Imipenem/cilastatin; Text classification technology; Real world study;
- Series：
(E) Medicine ＆ Public Health
- Subject：
Pharmaceutics
- Classification Code：
R969.3
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