Research Progress on the Stability of LigustilideChinese Full Text
HOU Xiaoying;GAO Fan;DU Lidong;WANG Ruiqiong;WU Guotai;School of Pharmacy, Gansu University of Traditional Chinese Medicine;Longyao Industry Innovation Research Institute;Gansu Provincial Key Laboratory of Pharmacology and Toxicology of Traditional Chinese Medicine;Collaborative Innovation Center for Northwest Chinese and Tibetan Medicine;
Abstract: Ligustilide(LIG) is a phthalide compound found in Angelica sinensis(Oliv.) Diels and Ligusticum chuanxiong Hort, which has a wide range of pharmacological activities in clinical practice, including anti-inflammatory, antioxidant, analgesic, anti-tumor, neuroprotective, and vascular protective effects. However, LIG has poor stability and is easily affected by factors such as temperature, light, oxygen, pH value, and solvent type, leading to conformational changes. In addition, the low water solub... More
Keywords:
ligustilide; stability; structural modification; conversion mechanism; stabilization method;
- Series:
(E) Medicine & Public Health
- Subject:
Traditional Chinese Medicinal Herbs
- Classification Code:
R284
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