Effect of Jinhua Qinggan granules on novel coronavirus pneumonia in patients

Liu Zengli¹Li Xiuhui¹Gou Chunyan¹Li Li¹Luo Xiaolan¹Zhang Chun¹Zhang Yin¹Zhang Jiaying²Jin Aihua²Li Hongyan¹Zeng Yuan¹Li Tongzeng²Wang Xiaojun¹

1. Integrated Traditional Chinese and Western Medicine Center, Beijing YouAn Hospital, Capital Medical University 2. General Department of Infectious Diseases, Beijing YouAn Hospital, Capital Medical University

摘要：OBJECTIVE: To evaluate the effectiveness and safety of Jinhua Qinggan granules in the treatment of patients with novel coronavirus pneumonia（COVID-19）.METHODS: Eighty cases of COVID-19 diagnosed from January 24 to February 17, 2020 in Beijing YouAn Hospital Affiliated to Capital Medical University were retrospectively analyzed. All 80 patients received symptomatic and supportive treatment.Among them, 44 patients took Jinhua Qinggan granules（treatment group） within 24 h of admission, and the remaining 36 patients either did not take Jinhua Qinggan granules or took the granules for less than 2 d（control group）. In this study, we compared the duration of viral nucleic acid detection and of pneumonia absorption improvement between the two groups.RESULTS: Among the 80 cases, 37 were male（46%）and 43 were female（54%） with age ranging from15 to 86 years, with an average age of 51.19 years.The average duration of viral nucleic acid detection was（7 ± 4） d in the Jinhua Qinggan administration group and（10 ± 4） d for the control group（P =0.010）, following which, nucleic acid tests were negative. Of the two groups, 56.82% in the Jinhua Qinggan treatment group and 27.78% in the control group demonstrated negative nucleic acid tests within 7 d or less. The 7-day viral clearance rate was significantly higher in the Jinhua Qinggan group compared with the control group（P = 0.009）. Furthermore, the pneumonia recovery time indicated by chest CT was（8 ± 4） d in the Jinhua Qinggan group, which was significantly shorter than the control group, at（10 ± 5） d（P = 0.021）. No adverse reactions were found in the treatment group after taking this medicine.CONCLUSION: In patients with COVID-19, Jinhua Qinggan granules can effectively shorten the duration of nucleic acid detection and promote the absorption of pneumonia inflammatory exudate without obvious adverse reactions.

基金资助：

Supported by Beijing Traditional Chinese Medicine （TCM）Science and Technology Development Fund Project （Evidence-Based Medicine Study of Novel Coronavirus Pneumonia Treated with Integrated Traditional Chinese and Western Medicine Based on Database,No. YJ2020-02）； Scientific Research Emergency Project （Study on the Prevention and Treatment of 2019-nCoV with Traditional Chinese Medicine,No. 2020YFC0841500）； the Scientific and Technological Research Project of Novel Coronavirus Pneumonia in Beijing Hospital Management Center （Retrospective Analysis of Clinical Observation on the Treatment of Novel Coronavirus Pneumonia Based on the Combination of Traditional Chinese and Western Medicine）；

DOI：
10.19852/j.cnki.jtcm.2020.03.016
专辑：
医药卫生科技
专题：
中医学
分类号：
R259

手机阅读

即刻使用手机阅读

第一步
扫描二维码下载

"移动知网-全球学术快报"客户端

第二步
打开“全球学术快报”

点击首页左上角的扫描图标

第三步
扫描二维码

手机同步阅读本篇文献
HTML阅读
CAJ下载
PDF下载

下载手机APP用APP扫此码同步阅读该篇文章

下载：415 页码：467-472 页数：6 大小：555K

引文网络

参考文献
引证文献
共引文献
同被引文献
二级参考文献
二级引证文献
批量下载

文章目录

Effect of Jinhua Qinggan granules on novel coronavirus pneumonia in patients

Liu Zengli¹Li Xiuhui¹Gou Chunyan¹Li Li¹Luo Xiaolan¹Zhang Chun¹Zhang Yin¹Zhang Jiaying²Jin Aihua²Li Hongyan¹Zeng Yuan¹Li Tongzeng²Wang Xiaojun¹

1. Integrated Traditional Chinese and Western Medicine Center, Beijing YouAn Hospital, Capital Medical University 2. General Department of Infectious Diseases, Beijing YouAn Hospital, Capital Medical University

即刻使用手机阅读

引文网络

相关推荐

文章目录

Effect of Jinhua Qinggan granules on novel coronavirus pneumonia in patients

Liu Zengli1Li Xiuhui1Gou Chunyan1Li Li1Luo Xiaolan1Zhang Chun1Zhang Yin1Zhang Jiaying2Jin Aihua2Li Hongyan1Zeng Yuan1Li Tongzeng2Wang Xiaojun1

1. Integrated Traditional Chinese and Western Medicine Center, Beijing YouAn Hospital, Capital Medical University2. General Department of Infectious Diseases, Beijing YouAn Hospital, Capital Medical University

即刻使用手机阅读

引文网络

相关推荐

Liu Zengli¹Li Xiuhui¹Gou Chunyan¹Li Li¹Luo Xiaolan¹Zhang Chun¹Zhang Yin¹Zhang Jiaying²Jin Aihua²Li Hongyan¹Zeng Yuan¹Li Tongzeng²Wang Xiaojun¹

1. Integrated Traditional Chinese and Western Medicine Center, Beijing YouAn Hospital, Capital Medical University 2. General Department of Infectious Diseases, Beijing YouAn Hospital, Capital Medical University